Light4Lungs departs from current paradigms as bacterial infections will be treated by a breathable light source, thus:
(1) Without including any externally added drug it overcomes the multidrug resistance profile;
(2) With eliciting the therapeutic action by a breathable light source it avoids the use of invasive physical tethers.
The encompasses the development of particles with persistent luminescence, the aerosol technology for activation and delivery to the lungs, and the definition of the treatment parameters through toxicity and efficacy tests in clinically relevant models of respiratory infections. Its results have the potential to go beyond treatment of recalcitrant respiratory tract bacterial infections to other lung diseases and to other organs, enriching fields of healthcare, nanomedicine, materials science and nanotechnology.
The Consortium, with 8 partners from 4 countries, is highly interdisciplinary and synergetic, combining several different scientific areas from photonics to medicine, including materials chemistry, physical chemistry, photo-physics, pharmaceutics, photobiology and microbiology. Multidisciplinary teams will be assemble to ensure cross-talk between disciplines and specialists throughout the project.
Facts in brief
Exciting times are ahead for the Light4Lungs consortium! We recently had the pleasure of visiting Liverpool for our consortium meeting where we shared our latest research advances and engaged in fruitful discussions about the project's plans for the last year of...
ICREA Recognizes our project coordinator Dr Santi Nonell as an Outstanding Researcher in Experimental Sciences & Maths
We are thrilled to announce that our project coordinator, Dr Santi Nonell, has been recognised in the 14th edition of the ICREA Academia in the "Experimental Sciences & Maths" area with a five-year research grant to expand his AppLightChem group research...
On Wednesday, January 18th, 2023, the Light4Lungs consortium had its second review meeting with the European Commission. The project coordinator and the project partners reported on the scientific, management, communications and dissemination progress made...